Medical Co Morbidities in Patients of Frontal Temporal Dementia -A Hospital Based Study_Crimson Publishers
Medical Co Morbidities in Patients of Frontal Temporal Dementia -A Hospital Based Study by Manjunadh Muralleedharan in Research in Medical & Engineering Sciences
Crimson Publishers_RMES
Dementia is increasingly becoming a major healthcare challenge as the
population ages worldwide, with an estimated 25 million cases of
dementia
globally. The most common cause of dementia is Alzheimer’s disease (AD)
which affects approximately 5.4 million individuals in the United States
alone.
Following the identification of tau gene mutations in familial forms of
this disorder, there is increasing interest in genetic factors that may
predispose
to the disease. About 60% of patients with frontotemporal dementia have
no family history of dementia and are considered to be sporadic cases.
Genetic factors, such as apolipoprotein E genotype and the H1 haplotype
of the tau gene, have been inconsistently associated with the sporadic
form
of the disease. Frontotemporal dementia (FTD) includes most of these
conditions, and is characterized by specific behavioral changes,
frontotemporal
atrophy on CT or MRI, and the absence of senile plaques and
neurofibrillary tangles at postmortem examination. In view of paucity of
studies in the said
condition, we decided to work on this. This study was designed to find
out medical co morbidities in patients of front temporal dementia.
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