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Medical Co Morbidities in Patients of Frontal Temporal Dementia -A Hospital Based Study_Crimson Publishers

Medical Co Morbidities in Patients of Frontal Temporal Dementia -A Hospital Based Study by Manjunadh Muralleedharan in Research in Medical & Engineering Sciences


  
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Dementia is increasingly becoming a major healthcare challenge as the population ages worldwide, with an estimated 25 million cases of dementia globally. The most common cause of dementia is Alzheimer’s disease (AD) which affects approximately 5.4 million individuals in the United States alone. Following the identification of tau gene mutations in familial forms of this disorder, there is increasing interest in genetic factors that may predispose to the disease. About 60% of patients with frontotemporal dementia have no family history of dementia and are considered to be sporadic cases. Genetic factors, such as apolipoprotein E genotype and the H1 haplotype of the tau gene, have been inconsistently associated with the sporadic form of the disease. Frontotemporal dementia (FTD) includes most of these conditions, and is characterized by specific behavioral changes, frontotemporal atrophy on CT or MRI, and the absence of senile plaques and neurofibrillary tangles at postmortem examination. In view of paucity of studies in the said condition, we decided to work on this. This study was designed to find out medical co morbidities in patients of front temporal dementia.

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