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Molecular Basis of Neural Memory Defining the Engram_ Crimson Publishers

Molecular Basis of Neural Memory Defining the Engram by Gerard Marx in Research in Medical & Engineering Sciences

A goal of neuroscientists is to identify the causal relationship between the functioning of neurons and the emergence of mental (psychic) states, such as emotions and memories. The notion that the basis for memory was due to physical changes in the brain, was first proposed by Richard Semon (~1900), who also coined the term “engram” to refer to the physical trace of memory. Elements of Semon’s concept are echoed nowadays in descriptions of “engram cells”, neurons which supposedly store and recall the memory trace. But none of these identify the code that instigates the emotive states experienced and remembered by neural systems.

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