Skip to main content

Analysis of Whole Blood Prothrombin Time/International Normalized Ratio Using Image Processing- Crimson Publishers

Analysis of Whole Blood Prothrombin Time/International Normalized Ratio Using Image Processing- Crimson Publishers



Purpose: Patients who had undergone mechanical heart valve replacements, who have atrial fibrillation or deep vein thrombosis, need drugs called oral anticoagulants to prevent blood clotting and need regular testing of Prothrombin Time/International Normalized Ratio. Conventional laboratory approaches are time consuming, need blood component separation and a regular visit to clinical labs. The burden of PT measurement on the clinical laboratory is huge globally, which raise need for point of care, quick and user-friendly device. Methods: In this study we have proposed a handheld device based on the image processing for the PT/INR detection. Cost effective disposable strips were fabricated using thromboplastin as reagent. Device and strips were tested for 100 samples in clinical set up as per the ISO standard 17593 “Clinical laboratory testing and in vitro medical devices - Requirements for in vitro monitoring systems for self-testing of oral anticoagulant therapy”. Results: Data was compared with the values obtained from clinical laboratory using automated coagulometer T Coag DT-100 (Trinity), and commercially available Point of Care (POC) device from Roche, Diagnostics. A correlation coefficient (r) of 0.87 & 0.77 was observed between lab vs Chitra device and Chitra device vs commercially available device, respectively. Conclusion: Clinically accepted correlation may be obtained after automation of the strip fabrication technique. The proposed device is cost effective and easy to operate and works on the novel approach of image processing. To best of our knowledge this is the first report on the image processing-based PT/INR monitoring device.

https://crimsonpublishers.com/rmes/fulltext/RMES.000711.php

For more open access journals in crimson publishers Please click on link: https://crimsonpublishers.com

For more articles on Research in Medical & Engineering Sciences Please click on link: https://crimsonpublishers.com/rmes/

Labels:

Comments

Post a Comment

Popular posts from this blog

Comparative Analysis of Knee Joint Replacement and Stem Cells Therapy Treatment for Knee Osteoarthritis Using Statistical Techniques- Crimson Publishers

Comparative Analysis of Knee Joint Replacement and Stem Cells Therapy Treatment for Knee Osteoarthritis Using Statistical Techniques- Crimson Publishers In order to evade surgical modality employed in knee osteoarthritis (OA), healthcare providers have developed knee cartilage regenerative techniques inducing stems cells. In this research, we compare two types of treatments to overcome knee osteoarthritis: knee replacement and stem cells therapy. The comparison on the basis of several aspects was established. The main concern of study was to assess recovery time, procedure cost, recovery rate, and invasiveness aspects on the basis of patients’ perceptions and reviews of experts. The results have effectively shown that the participants belonging from knee joint replacement surgery group were more exposed to invasiveness and had to suffer much more pain and complications as compared to the other group. Moreover, it was observed that participants belonging from stem cells therapy group ...
Post a Comment
Read more

Speed of Light and Gravity, 𝒈 = 𝑮𝒄𝟐/𝒓- Crimson Publishers

Speed of Light and Gravity, 𝒈 = 𝑮𝒄𝟐 / 𝒓- Crimson Publishers The speed of light and the lunar light year of the Earth have been used to calculate a centripetal acceleration. The results align exactly with gravity at the surface of the Earth or 9.8m/s2. It is thought that the electromagnetic field of the Earth extends in a circular path to the far edges of the solar system and the speed of light contributes to the centripetal acceleration experienced on Earth. The author concludes that electromagnetism is the driving force of gravity in the near- and far-fields of the solar system. https://crimsonpublishers.com/rmes/fulltext/RMES.000686.php For more open access journals in crimson publishers Please click on link: https://crimsonpublishers.com For more articles on Research in Medical & Engineering Sciences Please click on link: https://crimsonpublishers.com/rmes/
Post a Comment
Read more

Assessment of Attention-Deficit using a Dynamic-body Electronic Testing System- Crimson Publishers

Assessment of Attention-Deficit using a Dynamic-body Electronic Testing System- CrimsonPublishers This case study seeks to examine the changing nature of attention-deficit testing using a new wireless electronic tool called B-percept® protocol. The testing protocol consists to measure the participant’s perception of simple or complex visual (light), auditory (sound) and kinesthetic (vibration) stimuli, as triggered simultaneously or randomly. Tested with sportsmen and sedentary participants, the B-percept® system revealed that sportsmen accustomed to facing a changing human and/or physical environment are able to anticipate, to adapt and to react better-faster than sedentary participants. In future investigations, it might be possible to use B-percept® in a wider context where outcomes in the field of medicine, rehabilitation, disability or even training in specific task professions. https://crimsonpublishers.com/rmes/fulltext/RMES.000699.php For more open access journals in crim...
Post a Comment
Read more