Skip to main content

Research Progress of Matrix Metalloproteinases Deriving from Parasites- Crimson Publishers

Research Progress of Matrix Metalloproteinases Deriving from Parasites- Crimson Publishers



Matrix metalloproteinases (MMPs) is a large family. It is named because it needs metal ions like Ca2+, Zn2+as cofactors. Its family members have similar structures and are generally composed of five domains with different functions:

A. The hydrophobic signal peptide sequences;

B. The prepeptide region, mainly used to maintain the stability of the zymogen. When the region is cut off by exogenous enzymes, MMPs zymogen is activated.

C. The catalytic active region, having zinc ion binding sites, crucial for the enzyme catalysis.

D. The hinge region rich in proline.

E. The carboxyl terminal region, related to the substrate specificity of the enzyme [1].

https://crimsonpublishers.com/rmes/fulltext/RMES.000730.php

For more open access journals in crimson publishers Please click on link: https://crimsonpublishers.com

For more articles on Research in Medical & Engineering Sciences Please click on link: https://crimsonpublishers.com/rmes/

Labels:

Comments

Post a Comment

Popular posts from this blog

The Malachite Wen-Myeloid Sarcoma- Crimson Publishers

The Malachite Wen-Myeloid Sarcoma- Crimson Publishers   Contingent to World Health Organization (WHO) classification, myeloid sarcoma is denominated as a tumefaction comprised of myeloblasts amalgamated at an anatomical site divergent from the bone marrow which engenders distortion of normal tissue architecture. Generally, myeloid sarcoma is contemplated to be equivalent to and concurrent with acute myeloid leukaemia (AML), although lesions may occur in isolation. Additionally designated as granulocytic sarcoma, chloroma or extramedullary myeloid tumour, myeloid sarcoma categorically represents as a distinct tumefaction associated with architectural effacement of circumscribing soft tissue. Myeloid sarcoma may emerge as a de novo lesion or manifest as therapy related myeloid neoplasm or as disease progression within myeloproliferative neoplasm (MPN), myelodysplastic syndrome (MDS) or myelodysplastic / myeloproliferative neoplasm (MDS / MPN). In contrast, leukaemia cutis (LC) is...
Post a Comment
Read more

Use of Thymbra Species Spreading in the Flora of Turkey for Medicinal Purposes- Crimson Publishers

Use of Thymbra Species Spreading in the Flora of Turkey for Medicinal Purposes- Crimson Publishers In terms of richness of plant species, Turkey has an important position in the world. It contains about 9,000 plant species and 11,500 taxa. Moreover, more than 1,000 plant species are used as medicinal and aromatic plants in our country. Medicinal plants are mostly evaluated by gathering from nature. Lamiaceae family covers many well-known and economically important medicinal types such as mint, sage, balm, thyme, lavender, basil. These plants, with wide adaptation limits, are well adapted to temperate and tropical regions. Although it is found in the natural flora of almost every region in our country, the Aegean and Mediterranean regions have an important position in terms of endemic species of the family. Although there are many aromatic plant species belonging to the family Lamiaceae described as thyme in Turkey, especially species containing the essential oil carvacrol and thymol ...
Post a Comment
Read more

Novel Z-Nanofiber Sheet Mask of High Particle Collection Efficiency, Easy Breathing and Resistant To Water Vapor-Crimson Publishers

Novel Z-Nanofiber Sheet Mask of High Particle Collection Efficiency, Easy Breathing and Resistant To Water Vapor-Crimson Publishers Nonwoven fabric sheet is usually used as mask due to the comparatively high particles removal performance and ease of breathing. The diameter of the SARS-CoV-2 (COVID-19 virus), including various mutants, is considered to be about 50nm to 150nm which is a size that can be removed by the nonwoven fabric sheet mask according to the particle collection Air Filter Mechanism Theory (AFMT) as shown in Figure 1. The most disturbing problems are that large amounts of aerosols of various sizes, including many viruses, are released from the mouth by coughing, and those around the diameter of 300nm slip through the mask according to the AFMT. In order to solve the problem, the electric charge is usually given to the mask. Such modification, however, loses the effectiveness in the presence of water molecules in the breathing. Those are explained in Figure 2. https...
Post a Comment
Read more