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5-Methylcytosine DNA Methylation Patterns among Gut Predominate Commensal Escherichia coli and Lactobacilli from the Balbas and Mazekh Domestic Sheep Breeds-Crimson Publishers

5-MethylcytosineDNA Methylation Patterns among Gut Predominate Commensal Escherichia coli and Lactobacilli from the Balbas and Mazekh DomesticSheep Breeds by Pepoyan AZ in Research in Medical &Engineering Sciences


The aim of current investigation was to compare the 5-methylcytosine level in genomic DNA of commensal Escherichia coli and lactobacilli from the widely bred in Armenia sheep breeds-Mazekh and Balbas. The results revealed statistically confirmed differences in 5-methylcytosine methylation patterns of these bacteria in the bacterial isolates from Mazekh and Balbas sheep. The percentage of 5-methylcytosine of the genomic DNA was statistically higher for isolates from the Mazekh sheep in comparison with those of Balbas sheep (34.5±7.57 vs. 5.05±2.4, P <0.05). The Scatter Plot of relationship between cell surface hydrophobicity and genomic DNA’s 5-methylcytosine levels shows a moderately strong negative relationship between these characteristics of sheep gut isolates (Pearson R is -0.75). These results may be important for veterinary medicine and breeding programs.

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