Crimson Publishers-Research in Medical & Engineering Sciences

The Malachite Wen-Myeloid Sarcoma- Crimson Publishers   Contingent to World Health Organization (WHO) classification, myeloid sarcoma is denominated as a tumefaction comprised of myeloblasts amalgamated at an anatomical site divergent from the bone marrow which engenders distortion of normal tissue architecture. Generally, myeloid sarcoma is contemplated to be equivalent to and concurrent with acute myeloid leukaemia (AML), although lesions may occur in isolation. Additionally designated as granulocytic sarcoma, chloroma or extramedullary myeloid tumour, myeloid sarcoma categorically represents as a distinct tumefaction associated with architectural effacement of circumscribing soft tissue. Myeloid sarcoma may emerge as a de novo lesion or manifest as therapy related myeloid neoplasm or as disease progression within myeloproliferative neoplasm (MPN), myelodysplastic syndrome (MDS) or myelodysplastic / myeloproliferative neoplasm (MDS / MPN). In contrast, leukaemia cutis (LC) is...

Research Progress of Matrix Metalloproteinases Deriving from Parasites- Crimson Publishers Matrix metalloproteinases (MMPs) is a large family. It is named because it needs metal ions like Ca2+, Zn2+as cofactors. Its family members have similar structures and are generally composed of five domains with different functions: A. The hydrophobic signal peptide sequences; B. The prepeptide region, mainly used to maintain the stability of the zymogen. When the region is cut off by exogenous enzymes, MMPs zymogen is activated. C. The catalytic active region, having zinc ion binding sites, crucial for the enzyme catalysis. D. The hinge region rich in proline. E. The carboxyl terminal region, related to the substrate specificity of the enzyme [1]. https://crimsonpublishers.com/rmes/fulltext/RMES.000730.php For more open access journals in crimson publishers Please click on link: https://crimsonpublishers.com For more articles on Research in Medical & Engineering Sciences Pl...

Potential Value of Anti-inflammatory in the Prevention and Treatment of Deep Vein Thrombosis- Crimson Publishers The incidence of deep vein thrombosis (DVT) has been increasing in recent years. In addition to endothelial injury, blood stasis and hypercoagulability, thromb-inflammation describes the complex interplay between inflammation and coagulation that plays a critical role in the pathophysiology of DVT. Leukocytes, endothelial cells and platelets interact with each other, which promote inflammation and play a key role in DVT formation and development. Here, we review the relationship between inflammation and DVT, providing potential value for the development of anti-inflammatory drugs in the prevention and treatment of DVT. https://crimsonpublishers.com/rmes/fulltext/RMES.000728.php For more open access journals in crimson publishers Please click on link: https://crimsonpublishers.com For more articles on Research in Medical & Engineering Sciences Please click on link...

CHIDOS: Customized Hip Implant Design & Optimization Service- Crimson Publishers   CHIDOS is a web application that conducts artificial intelligence (AI) - empowered customization and Finite Element Analysis optimization (FEA) of additively-manufactured hip implants used in total hip arthroplasty. The medical practitioner only creates a patient profile, uploads the patient’s CT scans and confirms the anatomical landmarks that are necessary for the restoration of the patient’s hip biomechanics. Based on this information, CHIDOS automatically reconstructs the anatomy of the patient’s pelvic and femoral bones in a 3D digital environment, develops a patient-specific femoral stem as well as patient-specific surgical tools (i.e., broach/rasp, osteotomy guide) used in total hip arthroplasty, optimizes the implant’s design, and creates accompanying 3D documentation & 3D anatomical models of the hip joint, useful for preoperative planning and intra-operative guidance. The patien...